What Does My Brain MRI Mean?
A plain-language guide to the findings people most often see on their brain MRI report, and what a neurologist thinks about when interpreting them.
Reading your own MRI report can be unsettling. Words like ischemic, atrophy and chronic infarct sound alarming, and most reports are written for physicians rather than patients. The guide below explains the most common findings in plain language.
An important caveat. This page is educational. No finding on an MRI can be interpreted responsibly without your age, symptoms, examination and history. Nothing here is a diagnosis, and an MRI report alone is never enough to make one.
Common findings explained
What are white matter changes (white matter hyperintensities)?
Bright spots or patches on certain MRI sequences in the brain’s white matter, the wiring that connects regions. A few are common with normal aging. More extensive changes are most often linked to chronic effects of blood pressure and other vascular risk factors on small blood vessels, and less commonly to migraine, inflammation or other causes. The number, location and pattern matter, as does your history.
What is small vessel ischemic disease (microvascular changes)?
Radiologists use these terms for the same family of findings: changes caused by disease of the brain’s smallest arteries. It is closely tied to blood pressure, diabetes, cholesterol, smoking and age. It is not itself a diagnosis of dementia or stroke, but it is a signal that vascular brain health deserves attention.
What does brain atrophy mean?
Atrophy means a reduction in brain volume. Some volume loss is part of normal aging, and radiologists often note it when it is entirely appropriate for age. Atrophy that is more than expected, or concentrated in particular regions, can be more significant. Interpreting it requires knowing your age, symptoms and cognitive testing, not the report alone.
My MRI shows an “old stroke” or “chronic infarct” I never knew about. What now?
Silent infarcts are more common than most people realize and are a strong reason to review stroke risk factors carefully. The next step is not panic but a structured prevention review: blood pressure, cholesterol, heart rhythm, glucose, sleep apnea and lifestyle. See our stroke prevention page.
What is an incidental finding?
Something seen on the scan that was not what the scan was looking for: a small cyst, a benign-appearing lesion, a variation in anatomy. Most incidental findings are harmless. Some need follow-up imaging or a specialist opinion. A neurologist can help you understand which category yours falls into.
Can you diagnose me from my MRI report?
No, and neither can anyone else. An MRI is one piece of information. The same finding can be insignificant in one person and important in another depending on age, symptoms, examination and history. That is why a consultation looks at the whole picture, and why we ask for the images themselves when possible.
- Wardlaw JM, et al. Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration (STRIVE). Lancet Neurol. 2013;12:822-838.
- Debette S, Markus HS. The clinical importance of white matter hyperintensities on brain magnetic resonance imaging: systematic review and meta-analysis. BMJ. 2010;341:c3666.
- Morris Z, et al. Incidental findings on brain magnetic resonance imaging: systematic review and meta-analysis. BMJ. 2009;339:b3016.
Discuss Your MRI With a Neurologist
Bring the report and, if you can, the images. We will explain what they mean for you.